Lactones of Artemisia scoparia

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Antiulcerogenic activity of some sesquiterpene lactones isolated from Artemisia annua.

Artemisinin 1, dihydro-epideoxyarteannuin B 2 and deoxyartemisinin 3 were isolated from the sequiterpene lactone-enriched fraction obtained from the crude ethanolic extract of Artemisia annua L. These compounds were tested on ethanol and indomethacin-induced ulcer models. Compound 1 did not afford cytoprotection under the experimental models tested. Only compounds 2 and 3 decreased the ulcerati...

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Artemisia annua L.: evidence of sesquiterpene lactones’ fraction antinociceptive activity

BACKGROUND Artemisia annua L. has been used for many centuries in Chinese traditional medicine. Artemisinin, the active principle was first isolated and identified in the 1970s becoming the global back bone to the fight against malaria. Our research group previously developed an economic and ecological friendly process to obtain this compound. In the pursuit to also exploit the residue generate...

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Phytotoxicity of major constituents of the volatile oil from leaves of Artemisia scoparia Waldst. & Kit.

The phytotoxicity of the three major monoterpene constituents of the essential oil from leaves of Artemisia scoparia Waldst. & Kit. (redstem wormwood) was investigated. GC/GC-MS analysis revealed that the essential oil (yield 0.84%) is a complex mixture containing 19 monoterpenes, 7 sesquiterpenes and 15 other compounds--aliphatic alcohols, ketones, aromatic hydrocarbons and esters. The three m...

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Proficiencies of Artemisia scoparia against CCl4 induced DNA damages and renal toxicity in rat.

BACKGROUND Artemisia scoparia is traditionally used in the local system of medicine in kidney disorders. This study aimed at scrutinizing the nephroprotective prospective of A. scoparia methanol extract against carbon tetrachloride (CCl4) provoked DNA damages and oxidative stress in kidneys of rat. METHODS Dried aerial parts of A. scoparia were powdered and extracted with methanol to obtain t...

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Hepatoprotective effects of artemisia scoparia against carbon tetrachloride: an environmental contaminant.

The hepatoprotective activity of crude extract of artemisia scoparia (aerial parts) was investigated against experimentally produced hepatic damage using carbon tetrachloride (CCl4) as a model hepatotoxin. CCl4 at the dose of 1.5 ml/kg, produced liver damage in rats as manifested by the rise in serum levels of AST and ALT to 395 +/- 110 and 258 +/- 61 IU/l (mean +/- SEM; n = 10) respectively, c...

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ژورنال

عنوان ژورنال: Chemistry of Natural Compounds

سال: 1971

ISSN: 0009-3130,1573-8388

DOI: 10.1007/bf00569022